产品货号:
Z32949
中文名称:
AIF/AIFM1抗体
英文名称:
Anti-AIF/AIFM1 Antibody (Clone#OTI4E6)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AIF/AIFM1 Antibody (Clone#OTI4E6) |
指标别名 | AIF;AIFM1;Mitochondrion Marker;PDCD8 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | AIFM1 |
克隆号 | OTI4E6 |
抗体来源 | Mouse |
抗体类型 | IgG2a |
免疫原 | Human recombinant protein fragment corresponding to amino acids 134-483 of human AIFM1 (NP_001124318) produced in E.coli. |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | Apoptosis-inducing factor 1,mitochondrial,also known as AIF or PDCD8 is a protein that in humans is encoded by the AIFM1 gene.AIFM1 gene is mapped to Xq26.1 based on an alignment of the AIFM1 sequence with the genomic sequence.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells,and it is found in the mitochondrial intermembrane space in healthy cells.Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation.In addition,this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.Mutations in this gene cause combined oxidative phosphorylation deficiency 6,which results in a severe mitochondrial encephalomyopathy.A related pseudogene has been identified on chromosome 10. |
Uniprot ID | O95831 |
基因名全称 | apoptosis-inducing factor,mitochondrion-associated,1 |
蛋白名全称 | Apoptosis-inducing factor 1,mitochondrial |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:500 |
相关搜索:AIF/AIFM1抗体,AIF抗体,AIFM1单抗,Anti-AIF/AIFM1 Antibody (Clone#OTI4E6)